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Basant Kumar Patel
Associate Professor
Department of Biotechnology
basantkpatel@bt.iith.ac.in (Work)
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Publications - 22
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Publications (22)
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Publications (22)
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Book Chapter
TDP-43 proteinopathy mechanisms from non-mammalian model systems
V. Bharathi
,
A. Girdhar
and
Basant Kumar Patel
2022 | Elsevier
Articles
In Vitro Interaction of a C-Terminal Fragment of TDP-43 Protein with Human Serum Albumin Modulates Its Aggregation
S. Nirwal
,
P. Saravanan
,
...
,
Prabusankar Ganesan
and
Basant Kumar Patel
(8 authors)
2022 | American Chemical Society
Articles
Elevated constitutive expression of Hsp40 chaperone Sis1 reduces TDP-43 aggregation-induced oxidative stress in Ire1 pathway dependent-manner in yeast TDP-43 proteinopathy model of amyotrophic lateral sclerosis
V. Bharathi
,
A. Bajpai
,
...
,
Basant Kumar Patel
(4 authors)
2022 | Elsevier B.V.
Articles
Zn2+ modulates in vitro phase separation of TDP-432C and mutant TDP-432C-A315T C-terminal fragments of TDP-43 protein implicated in ALS and FTLD-TDP diseases
S. Preethi
,
V. Bharathi
and
Basant Kumar Patel
2021 | Elsevier B.V.
Articles
Role of CNC1 gene in TDP-43 aggregation-induced oxidative stress-mediated cell death in S. cerevisiae model of ALS
V. Bharathi
,
A. Girdhar
and
Basant Kumar Patel
2021 | Elsevier B.V.
Articles
Pharmaceutical acetylation can modulate the amyloidogenicity of human serum albumin
V. Bharathi
,
R.R. Manglunia
,
...
,
Basant Kumar Patel
(5 authors)
2021 | National Institute of Science Communication and Information Resources
Articles
Amyloid-like aggregation of bovine serum albumin at physiological temperature induced by cross-seeding effect of HEWL amyloid aggregates
S. Nirwal
,
V. Bharathi
and
Basant Kumar Patel
2021 | Elsevier B.V.
Articles
Computational insights into mechanism of AIM4-mediated inhibition of aggregation of TDP-43 protein implicated in ALS and evidence for in vitro inhibition of liquid-liquid phase separation (LLPS) of TDP-432C-A315T by AIM4
A. Girdhar
,
V. Bharathi
,
...
,
Rajakumara Eerappa
,
Basant Kumar Patel
and
Prabusankar Ganesan
(11 authors)
2020 | Elsevier B.V.
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PDF
Postprint
Reviews
Molecular mechanisms of TDP-43 misfolding and pathology in amyotrophic lateral sclerosis
A. Prasad
,
V. Bharathi
,
...
,
Basant Kumar Patel
(5 authors)
2019 | Frontiers Media S.A.
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PDF
Publisher Copy
Articles
Q-rich yeast prion [PSI+] accelerates aggregation of transthyretin, a non-q-rich human protein
M. Verma
,
A. Girdhar
,
Basant Kumar Patel
,
...
,
V. Taneja
(6 authors)
2018 | Frontiers Media S.A.
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PDF
Publisher Copy
Articles
The amyloidogenicity of a C-terminal region of TDP-43 implicated in Amyotrophic Lateral Sclerosis can be affected by anions, acetylation and homodimerization
A. Prasad
,
V. Sivalingam
,
...
,
Basant Kumar Patel
(5 authors)
2018 | Elsevier B.V.
Articles
Overexpression of the essential Sis1 chaperone reduces TDP-43 effects on toxicity and proteolysis
S.-K. Park
,
J.Y. Hong
,
...
,
Basant Kumar Patel
,
...
,
S.W. Liebman
(10 authors)
2017 | Public Library of Science
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PDF
Publisher Copy
Articles
Wild-type hen egg white lysozyme aggregation in vitro can form self-seeding amyloid conformational variants
V. Sivalingam
,
N.L. Prasanna
,
...
,
Basant Kumar Patel
(5 authors)
2016 | Elsevier B.V.
Articles
Recombinant human semenogelin-1 (Sg1) and Sg1 (1-159) form detergent stable amyloid like aggregates in vitro
N. Sharma
,
S. Vishwanath
and
Basant Kumar Patel
2016 | Bentham Science Publishers
Articles
Imidazolium tagged acridines: Synthesis, characterization and applications in DNA binding and anti-microbial activities
G. Raju
,
S. Vishwanath
,
...
,
Basant Kumar Patel
and
Prabusankar Ganesan
(5 authors)
2016 | Elsevier
Articles
Use of ade1 and ade2 mutations for development of a versatile red/white colour assay of amyloid-induced oxidative stress in saccharomyces cerevisiae
V. Bharathi
,
A. Girdhar
,
...
,
Basant Kumar Patel
(6 authors)
2016 | John Wiley and Sons Ltd
Articles
An acridine derivative, [4,5-bis{(N-carboxy methyl imidazolium)methyl}acridine] dibromide, shows anti-TDP-43 aggregation effect in ALS disease models
A. Prasad
,
G. Raju
,
...
,
Basant Kumar Patel
and
Prabusankar Ganesan
(9 authors)
2016 | Nature Publishing Group
Articles
Familial mutations in fibrinogen Aα (FGA) chain identified in renal amyloidosis increase in vitro amyloidogenicity of FGA fragment
V. Sivalingam
and
Basant Kumar Patel
2016 | Elsevier B.V.
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PDF
Postprint
Articles
New insights into in vitro amyloidogenic properties of human serum albumin suggest considerations for therapeutic precautions
N. Sharma
,
V. Sivalingam
,
...
,
Basant Kumar Patel
(7 authors)
2015 | Wiley Blackwell
Articles
The yeast global transcriptional co-repressor protein Cyc8 can propagate as a prion
Basant Kumar Patel
,
J. Gavin-Smyth
and
S.W. Liebman
2009
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PDF
Postprint
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