Short and concise syntheses of the hexahydroindene cores of the antibiotics indanomycin (X-14547 A) and stawamycin are presented. Key methods used are an asymmetric iridium-catalyzed allylic alkylation, a modified Julia olefination, a Suzuki-Miyaura coupling, and an intramolecular Diels-Alder reaction. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Satyanarayana Gedu

Department of Chemistry

M. Gärtner

S. Förster

G. Helmchen

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IIT Hyderabad

Chemistry - A European Journal

Syntheses of the hexahydroindene cores of indanomycin and stawamycin by combinations of iridium-catalyzed asymmetric allylic alkylations and intramolecular diels-alder reactions