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Superacid-promoted dual C-C bond formation by Friedel-Crafts alkylation/acylation of cinnamate esters: Synthesis of indanones
B.V. Ramulu, P. Niharika,
Published in Georg Thieme Verlag
2015
Volume: 47
   
Issue: 9
Pages: 1255 - 1268
Abstract
Dual C-C bond formation was accomplished in one pot for the synthesis of a wide variety of indanones mediated by triflic acid. The reaction proceeds via an initial Michael-addition-type Friedel-Crafts alkylation followed by intramolecular acylation (cyclization). Significantly, the method was also successfully employed on more reactive β-diarylcinnamates using slightly different conditions © Georg Thieme Verlag Stuttgart New York Synthesis 2015.
About the journal
JournalSynthesis (Germany)
PublisherGeorg Thieme Verlag
ISSN00397881