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Superacid-promoted dual C-C bond formation by Friedel-Crafts alkylation and acylation of ethyl cinnamates: Synthesis of indanones
B. Venkat Ramulu, A. Gopi Krishna Reddy,
Published in
2013
Volume: 24
   
Issue: 7
Pages: 868 - 872
Abstract
A superacid (triflic acid) promoted dual C-C bond formation via intermolecular Friedel-Crafts alkylation (Michael addition type) and intramolecular acylation for the efficient synthesis of 3-substituted indan-1-ones is presented. This method was successful in activating ethyl cinnamates towards dual aromatic electrophilic substitution. Moreover, it enabled us to synthesize novel spirotetracyclic systems. © Georg Thieme Verlag Stuttgart · New York.
About the journal
JournalSynlett
ISSN09365214