While modeling the industrial grinding circuits (IGCs), the presence of uncertain process parameters intensifies the level of difficulty, especially when the objectives aimed to be optimized are conflicting. In this chapter, considering various sources of uncertainties, a three objective IGC stochastic optimization problem is solved by means of robust optimization (RO) approach. Conventionally, researchers adopted specific geometric shape based uncertainty sets like box, diamond, and so on, for generating samples from the uncertain variable space. Nonetheless, in real scenarios, since the uncertain parameter data may be sparse and might not necessarily follow any distribution, the existing uncertainty sets may lead to conservative solutions. Thus, a new data based sampling technique for RO is presented, which utilizes unsupervised machine learning and novel generative modeling framework for identifying the intended space more accurately and sampling in the desired regions of uncertainty. An industrial grinding circuit, consisting of three decision variables, 10 parameters that depict the uncertainties in the model and feed stream and three conflicting objectives based on productivity, quality and energy savings in the process, is used to demonstrate the effectiveness of the novel framework followed by comparison studies. © 2023 Elsevier Inc. All rights reserved.