The mammalian olfactory system learns rapidly from very few examples, presented in unpredictable online sequences, and then recognizes these learned odors under conditions of substantial interference without exhibiting catastrophic forgetting. We have developed a brain-mimetic algorithm that replicates these properties, provided that sensory inputs adhere to a common statistical structure. However, in natural, unregulated environments, this constraint cannot be assured. We here present a series of signal conditioning steps, inspired by the mammalian olfactory system, that transform diverse sensory inputs into a regularized statistical structure to which the learning network can be tuned. This preprocessing enables a single instantiated network to be applied to widely diverse classification tasks and datasets - here including gas sensor data, remote sensing from spectral characteristics, and multilabel hierarchical identification of wild species - without adjusting network hyperparameters. © 2019 Copyright held by the owner/author(s). Publication rights licensed to ACM.