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N-dealkylative SNAr reaction using aromatic halides: Synthesis of dihydrobenzoxazine and tetrahydrobenzoxazepine derivatives
M.A. Pathan,
Published in Elsevier Ltd
2017
Volume: 73
   
Issue: 41
Pages: 6008 - 6020
Abstract
An efficient protocol for the synthesis of dihydrobenzoxazine and tetrahydrobenzoxazepine derivatives has been developed using haloarenes involving N-dealkylative SNAr reaction. The method employs a wide variety of substrates and features the formation of C[sbnd]O and C[sbnd]N bonds in one-pot fashion. The products thus generated have been further transformed to m-terphenyls by using Suzuki coupling reaction. © 2017 Elsevier Ltd
About the journal
JournalData powered by TypesetTetrahedron
PublisherData powered by TypesetElsevier Ltd
ISSN00404020