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Microwave-Assisted Domino Palladium Catalysis in Water: A Diverse Synthesis of 3,3′-Disubstituted Heterocyclic Compounds
K. Ramesh, S. Basuli,
Published in Wiley-VCH Verlag
2018
Volume: 2018
   
Issue: 19
Pages: 2171 - 2177
Abstract
An environmentally benign microwave-assisted domino [Pd]-catalyzed reaction, for the efficient and diverse synthesis of 3,3′-disubstituted indolines, oxindoles, and dihydrobenzofurans, is presented. Significantly, water served as the sole green solvent and the strategy displayed an excellent functional-group tolerance. Remarkably, the process was also amenable to unmasked functional groups and furnished the products, in very good to almost quantitative yields. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
About the journal
JournalData powered by TypesetEuropean Journal of Organic Chemistry
PublisherData powered by TypesetWiley-VCH Verlag
ISSN1434193X