The Minamata Convention on Mercury (ref. 1) is a global treaty to protect human and environmental health from adverse effects of the toxic element mercury and its compounds. During the Third Conference of Parties (COP-3) in November 2019, elimination of the use of dental amalgam in oral health care was discussed. Dental amalgam is one of the most commonly used restorative materials in oral health care due to its strength and longevity (ref. 2). However, the use of mercury in an amalgam adds to global environmental mercury pollution and can contribute to adverse health effects on humans and other organisms. The outcomes of the COP-3 meeting included a call for information on the availability at a national scale, the economic and technical feasibility of alternatives, and the associated risks or benefits. In this feature, we discuss the risks and benefits of dental amalgam, the global tracking of availability and procurement, and the implications and realities for global phase out. We suggest a better accounting of mercury use in dental amalgam is needed with sales being made only to registered practitioners via a Know Your Customer approach. © 2020 American Chemical Society.