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KOtBu-Mediated Domino Isomerization and Functionalization of Aromatic Allylic Alcohols
B. Suchand,
Published in Wiley-VCH Verlag
2017
Volume: 2017
   
Issue: 26
Pages: 3886 - 3895
Abstract
Transition-metal- as well as ligand-free base-mediated domino isomerization and alkylation of allylic alcohols is presented. This protocol features the conversion of simple allylic alcohols into the corresponding ketones through isomerization in the presence of a simple base. Significantly, these in situ generated ketones subsequently undergo alkylation with styrenes as electrophiles, in a domino one-pot fashion, as an atom- and step-economical chemical process. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
About the journal
JournalData powered by TypesetEuropean Journal of Organic Chemistry
PublisherData powered by TypesetWiley-VCH Verlag
ISSN1434193X