The present paper empirically analyzes the structural change in world trade over the last two decades by examining trade integration, leadership, and regionalization through a network model. We selected 50 countries encompassing both developed and developing nations and grouped them into 9 regions for 1990, 1992, 2000, 2010, and 2017. We have undertaken two principal analyses: (i) trade intensity indices and regionalization and (ii) linking trade intensity with network analysis. Therefore, this paper reaches a trade-off condition. The major findings of the study are as follows: (i) regional integration is stronger and has increased over the years; (ii) trade regionalization is primarily dominated by developed regions; (iii) trade liberalization has reduced the gap between the center and periphery; (iv) emerging Asian economies have developed as leaders and export hubs of goods in the global market; (v) trade liberalization has transformed and reshaped the world trade structure; and (vi) trade liberalization has not driven the lessening geodesic distance and transport costs from trade, and thus, there are no major gains for many countries. © 2020-Center for Economic Integration, Sejong Institution, Sejong University, All Rights Reserved.