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Gold(I)-Catalyzed Direct Stereoselective Synthesis of Deoxyglycosides from Glycals
C. Palo-Nieto, , M.C. Galan
Published in American Chemical Society
2017
PMID: 28934850
Volume: 139
   
Issue: 40
Pages: 14041 - 14044
Abstract
Au(I) in combination with AgOTf enables the unprecedented direct and α-stereoselective catalytic synthesis of deoxyglycosides from glycals. Mechanistic investigations suggest that the reaction proceeds via Au(I)-catalyzed hydrofunctionalization of the enol ether glycoside. The room temperature reaction is high yielding and amenable to a wide range of glycal donors and OH nucleophiles. © 2017 American Chemical Society.
About the journal
JournalData powered by TypesetJournal of the American Chemical Society
PublisherData powered by TypesetAmerican Chemical Society
ISSN00027863