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Effect of dean flows on sub-micron particles in low aspect ratio microchannels - analysis of dff
, L.Y.L. Yung
Published in Chemical and Biological Microsystems Society
2020
Pages: 242 - 243
Abstract
We present an analysis of the microfluidic Dean flow fractionation (DFF) method in low aspect-ratio spiral chip for high concentrations (> 106 particles /mL) of sub-micron (1-3 μm) particles. We systematically analyze the particle stream profile (i.e. thickness and distance from the channel wall) as a function of downstream channel length for step-wise increase in the fluid velocity and the flow rate ratio (FRR) of the particles to the sheath fluid. © 2020 CBMS-0001
About the journal
JournalMicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society