In this paper we consider a multi-user spatial multiplexing (SM) cellular network, where Nt streams are transmitted to Nt users in the cell. Specifically, we obtain the coverage and rate expressions for a system employing zero-forcing (ZF) receiver. Compared to single stream transmission (SST), it is interesting to see that SM degrades the rate for a notable percentage of users. For the case of two and four receiver antennas, the increase in mean rate of SM is modest compared to single stream transmission (SST) while SST provides a gain over SM for cell edge users. © 2013 IEEE.