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Chemo-selective Rh-catalysed hydrogenation of azides into amines
M. Ghirardello, H. Ledru, , M.C. Galan
Published in Elsevier Ltd
2020
PMID: 32062397
Volume: 489
   
Abstract
Rh/Al2O3 can be used as an effective chemo-selective reductive catalyst that combines the mild conditions of catalytic hydrogenation with high selectivity for azide moieties in the presence of other hydrogenolysis labile groups such as benzyl and benzyloxycarbonyl functionalities. The practicality of this strategy is exemplified with a range of azide-containing carbohydrate and amino acid derivatives. © 2020
About the journal
JournalData powered by TypesetCarbohydrate Research
PublisherData powered by TypesetElsevier Ltd
ISSN00086215