This editorial considers the problem of automatic identification of choriocapillaris in 2D-optical coherence tomography images. Firstly, the major challenges in automating the process are presented. Subsequently, the authors present an overview of current methods in the automatic segmentation of 2D-optical coherence tomography images. Lastly, the authors close with a discussion on a recent algorithm for the automated identification of choriocapillaris based on the identification of the retinal pigment epithelial layer and the region in its immediate neighborhood, and its capabilities. © 2014 Informa UK, Ltd.