Three-dimensional (3D) tissue printing is the approach to printing millimeter- to centimeter-sized biological constructs that include several cell types and biomaterials simultaneously. Biomimetic 3D tissue printing relies on mimicking key features of the extracellular matrix (ECM), either physically or chemically, for successful tissue regeneration. In native tissue, the ECM provides cells with a variety of physical, chemical, and biological cues that affect cell growth and function. Numerous methods are being developed to create 3D tissue scaffolds with control over their physical and mechanical properties, cell adhesion, and the spatiotemporal release of growth factors to mimic the physicochemical attributes of the ECM.We herein present an overview of a variety of 3D tissue printing methods that are currently used to produce 3D tissue for implantation, modify their surfaces with biochemical ligands, incorporate growth factors, and control their nano- and microscale geometry to create biomimetic scaffolds. Furthermore, various innovative attempts in biomimetic 3D tissue printing based on either physical or chemical approaches for production of tissue or organs are discussed.A basic understanding of the entire spectrum of biomimetic 3D tissue printing provides a pragmatic insight into how it can potentially be used in diverse tissue engineering applications and regenerative medicine. © 2014 by World Scientific Publishing Co. Pte. Ltd.