This chapter gives an overview of the various thermochemical routes for the conversion of triglycerides to biofuels. The transesterification, thermal and catalytic cracking, and hydrodeoxygenation are the main thermochemical processes for manufacturing biofuels from triglycerides. The transesterification of triglycerides with methanol produces fatty acid methyl esters, known as biodiesel. The thermal and catalytic cracking of triglycerides produces hydrocarbons in the range of gasoline, jet fuel, and diesel. The cracking routes are, however, associated with the drawback of low yield of biofuel and catalyst deactivation due to the coke deposition on the catalyst. The hydrodeoxygenation is the most potential route to convert triglycerides to diesel-range hydrocarbons, known as green diesel. In this route, the oxygen is eliminated as water and CO. The green diesel is also fully compatible with the existing diesel engine. This chapter provides a detailed description of these processes, including operating conditions, reaction mechanism, catalysts, and technoeconomic feasibility. © 2020 Nova Science Publishers, Inc. All rights reserved.