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Backbone chemical shift assignments of the acyl-acyl carrier protein intermediates of the fatty acid biosynthesis pathway of Plasmodium falciparum
S.K. Upadhyay, , N. Surolia, A. Surolia, M. Sundd
Published in Springer Netherlands
2010
Volume: 4
   
Issue: 1
Pages: 83 - 85
Abstract
We report the backbone chemical shift assignments of the acyl-acyl carrier protein (ACP) intermediates of the fatty acid biosynthesis pathway of Plasmodium falciparum. The acyl-ACP intermediates butyryl (C4), -octanoyl (C8), -decanoyl (C10), -dodecanoyl (C12) and -tetradecanoyl (C14)-ACPs display marked changes in backbone HN, Cα and Cβ chemical shifts as a result of acyl chain insertion into the hydrophobic core. Chemical shift changes cast light on the mechanism of expansion of the acyl carrier protein core. © 2010 Springer Science+Business Media B.V.
About the journal
JournalData powered by TypesetBiomolecular NMR Assignments
PublisherData powered by TypesetSpringer Netherlands
ISSN18742718