Reliability and delay of a single cluster wireless network is well analysed in the literature. Multi-hop communication over the number of clusters is essential to scale the network. Analytical model for reliability and end-to-end delay optimization for multi-hop clustered network is presented in this paper. Proposed model is a three dimensional markov chain. Three dimensions of markov model are the adaptable mac parameters of CSMA-CA. Model assumes wakeup rates for each cluster. Results show that reliability and delay are significantly improved than previous analytical models proposed. It has been observed that overall reliability of multi-hop link is improved, with reduction in end-to-end delay is reduced even at lower wakeup rates of a cluster. © 2014 IEEE.