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An unusual formation of diarylmethane scaffolds from 4-(halomethyl)cyclohex-2-enone derivatives
K.R. Babu,
Published in Elsevier Ltd
2015
Volume: 56
   
Issue: 27
Pages: 4067 - 4070
Abstract
Abstract A facile and efficient base promoted one-pot dimerization of halo cyclohexene derivatives leading to a de novo synthesis of biologically important diarylmethane and diarylmethanone derivatives is reported. A plausible mechanism for the unexpected formation of the title compounds involves dehydrohalogenation, 1,6-conjugate addition, subsequent aromatization through C-C bond cleavage and dehydrohalogenation. © 2015 Elsevier Ltd.
About the journal
JournalData powered by TypesetTetrahedron Letters
PublisherData powered by TypesetElsevier Ltd
ISSN00404039