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An electrochemical cascade process: synthesis of 3-selenylindoles from 2-alkynylanilines with diselenides
A.B. Dapkekar,
Published in Royal Society of Chemistry
2023
PMID: 37351598
Volume: 59
   
Issue: 56
Pages: 8719 - 8722
Abstract
Substituted organoselenium compounds are crucial structural motifs in pharmaceutical molecules. Herein, we report a metal, oxidant, and base-free electrochemical approach to access 3-selenylindoles through an oxidative cyclization of 2-alkynylanilines with diselenides. This environmentally friendly approach demonstrates a wide range of substrate scope under mild reaction conditions in an electrochemical undivided cell setup. © 2023 The Royal Society of Chemistry.
About the journal
JournalChemical Communications
PublisherRoyal Society of Chemistry
ISSN13597345