An efficient three-step strategy for the synthesis of functionalized flavans, starting from readily available 2-bromoiodobenzenes and aryl vinyl alcohols, is presented and successfully extended to benzoxepine. An intermolecular [Pd]-catalyzed C-C and an intramolecular [Cu]-catalyzed C-O bond formations have been employed as key transformations of the strategy. © 2012 Elsevier Ltd. All rights reserved.

Satyanarayana Gedu

Department of Chemistry

B. Suchand

J. Krishna

B. Venkat Ramulu

D. Dibyendu

A. Gopi Krishna Reddy

L. Mahendar

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Tetrahedron Letters

An efficient intermolecular [Pd]-catalyzed C-C and intramolecular [Cu]-catalyzed C-O bonds formation: Synthesis of functionalized flavans and benzoxepine

Journal	Tetrahedron Letters
ISSN	00404039