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A TBADT photocatalyst-enabled radical-induced cyclization pathway to access functionalized dihydrobenzofurans
P.S. Gowda, D.S. Sharada,
Published in Royal Society of Chemistry
2023
PMID: 37403566
Abstract
Herein, this work describes a photoinduced visible light-mediated radical cyclization for constructing dihydrobenzofuran (DHB) scaffolds. Notably, this cascade photochemical process is tolerable with various aromatic aldehydes and diverse alkynyl aryl ethers and proceeds via an intramolecular 1,5-hydrogen atom transfer (HAT) pathway. Significantly, acyl C-H activation under mild conditions has been achieved without the use of additives or reagents. The photocatalyst, tetrabutylammonium decatungstate (TBADT), plays an important role in the present strategy by facilitating the well-known hydrogen atom transfer during the course of the reaction. © 2023 The Royal Society of Chemistry.
About the journal
JournalChemical Communications
PublisherRoyal Society of Chemistry
ISSN13597345