A Microstrip Patch antenna resonating at 2.47 GHz is proposed which is made of a silicon substrate. The proposed antenna has been designed for biomedical applications in human body. The substrate chosen has an ease of fabrication and biocompatibility compared to other semiconductors. The designed antenna is being aimed to be utilized on skin as well as inside the body taking into consideration of tissue parameters. The directivity, gain and radiation efficiency is high as compared to antenna made on RO3730 of dielectric constant 3. © 2012 IEEE.